Zebrafish reduce drug discovery gridlock
نویسندگان
چکیده
منابع مشابه
Zebrafish: from disease modeling to drug discovery.
The study of zebrafish, a leading model organism for developmental biology, is rapidly expanding to include human disease. Zebrafish models based on known disease mechanisms have been developed in several therapeutic areas, including blood diseases, diabetes, muscular dystrophy, neurodegenerative disease, angiogenesis and lipid metabolism. This review summarizes recent progress in disease model...
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The increasing cost of bringing new drugs to the market is a driving force for the exploration of new technologies that allow high-content screening and earlier decisionmaking and prioritisation in drug discovery. As a vertebrate model organism highly relevant to human development and disease, the zebrafish has rapidly risen to a position of prominence in academic research laboratories – a deve...
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ژورنال
عنوان ژورنال: Nature Reviews Drug Discovery
سال: 2004
ISSN: 1474-1776,1474-1784
DOI: 10.1038/nrd1398